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The delayed bloodstream clearance of Plasmodium falciparum parasites after M5717 treatment is attributable to the inability to modify their red blood cell hosts.

Schneider MP, Looker O, Rebelo M, Khoury DS, Dixon MWA, Oeuvray C, Crabb BS, McCarthy J, Gilson PR

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  • Journal Frontiers in cellular and infection microbiology

  • Published 29 Jun 2023

  • Volume 13

  • Pagination 1211613

  • DOI 10.3389/fcimb.2023.1211613

Abstract

persistence of M5717 treated iRBCs in the bloodstream is likely due to reduced cytoadherence and splenic clearance.