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COVID-19 antigens for PoC test development

Our group has extensive expertise in the expression of viral glycoprotein antigens, manipulation of protein sequences to enhance expression and optimisation of purification methods. In this project we will express both the spike and nucleoproteins of COVID-19 and other coronaviruses. These antigens will contribute to the development of a COVID-19 point-of-care diagnostic test.

We will contribute to the development of a point-of-care (PoC) COVID-19 test by providing novel technology to alter antigen structure and enhance the sensitivity of PoC tests that can be monitored by biolayer interferometry.

We have commenced a large project to express both the spike and nucleoproteins of COVID-19 and other coronaviruses including SARS, MERS, OC43, 229E, NL63, and HKU1. The antigens will be provided to Burnet’s Global Health Diagnostics Development Group for development of a COVID-19 point-of-care (PoC) diagnostic test.

Heidi

Professor Heidi Drummer

Contact Professor Heidi Drummer for more information about this project.

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Funding
Partners

  • Victorian Government (part of $1m for Diagnostics Development)

Project
Team

Meet the project team. Together, we are translating research into better health, for all.