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Managing HIV. Part 3. Mechanisms of disease. 3.2 How HIV produces immune deficiency.

Ffrench R, Stewart GJ, Penny R, Levy JA

  • Journal The Medical journal of Australia

  • Published 26 Jun 1996

  • Volume 164

  • ISSUE 3

  • Pagination 166-71


Initially, the immune system controls HIV infection, but over time the virus depletes the population of CD4+ T cells and disturbs the homoeostasis and function of other cells in the immune system. Extensive destruction of the immune system eventually leaves the body defenceless.