Systematic Community-Wide Engagement and Elimination Project for Tuberculosis (SWEEP-TB) in Daru, Western Province, Papua New Guinea
SWEEP-TB is a community-centred public health project conducted by the Western Province tuberculosis (TB) partnership that will screen all residents of Daru, Papua New Guinea to detect, treat and prevent TB, using a comprehensive package of existing and novel tools.
Embedded implementation research will provide an evaluation framework to assess the impact on age-related TB incidence of tuberculosis, monitor uptake and acceptability and develop a scalable model of care.
Dr Aung explains how community screening is finding hidden TB cases
Presenter: So joining us this morning [from] the Burnet Institute's SWEEP program is Dr. Aung Aung. He joins us on the line from Daru. With that I say gutpela moning Dr. Aung and welcome to Pacific Beat.
Dr Aung: Hi good morning. Uh thank you for having me. Absolutely. Uh doctor can you just firstly maybe tell us what has been the impact of TB on PNG? Well, the impact of TB on PNG is quite huge especially in the western province and where I work in Daru which as you said earlier there is a TB outbreak in the past that has led to all these challenges and then now it's end up with our community screening which is called SWEEP-TB in the last 2 years. But before this project though doctor what were you seeing in terms of numbers like how many people were actually affected by TB? The number of patients affected every year is quite significant let's say like 600 to 700 every year in that area but uh it's not only about the number it's about like a magnitude impact of the population here so it is quite big compared to the other national prevalence as well as other countries.
Presenter: Doctor, you talk about the program that you're part of which is SWEEP-TB. What exactly is that and how has this project I suppose been any different from maybe other approaches?
Dr. Aung: Okay, so SWEEP-TB is actually we want to screen, treat and prevent the whole population in Daru Island. So we want to integrate this TB care into the community find the cases as early as they can before they are getting sick to come to the health centre for the further care. So we also want to be a look at community capability workforce diagnosis system referral linkage. So that is the the main aims of the SWEEP-TB and that is actually not quite very different than other settings that is what the WHO recommended for community screening for the high burden setting. So that's what we have implemented in Daru Island.
Presenter: Can you take us through how that testing looks like when you are screening your clients there?
Dr. Aung: Okay. So we try to reach the every single people on the island. So that is why we use like community engagement and we use house to house screening and we also utilise X-rays and also like a rapid diagnosis test. So on a normal day like we started with the community engagement within with our team and also community leaders and the members and then we distribute the message and the team goes house-to-house door-to-door and we do that symptomatic screening in the house giving some education and then they are referred to a sort of central location close to their houses for the further checkup like X-ray examination and also if they are symptomatic or if they are have some they are presumptive we collect sputum and then after that the result come back either they are a TTP or not so this is a process that we normally do in a normal day.
Presenter: Doctor so it's very much a community approach I can see you're going door-to-door. What has been the response then from the community because you know sometimes maybe stigma plays a big factor into people coming forward right is that the case sometimes.
Dr. Aung: Well, I think people have different ideas and then they have their own concept in that things. So we also have experience with community engagement. So we understand what people will think of. So that's why we strategise our community engagement messages that TB is the thing that we are coming to help them. We're coming to help to screen if they have the disease we can treat them and we can prevent them. So that is what we also strategise ourself our community engagement strategy to reach to the people to reduce the stigma to to make them aware to understand the disease.
Presenter: Nice. Now with those who have been diagnosed with TB I understand some actually had no symptoms at all. So I'm wondering how critical is this in terms of stopping transmission?
Dr. Aung: Well, I think this is the biggest thing that we found out. So as you as you we have like more than half of the total active cases that we found are not showing any symptoms. This is quite significant because it is if we rely on the people who are sick and who came to the health facilities for the care that will be too late and that will be like they will be transmitting the disease in a community. So that this is the main point that we have to we found out and then we have helped them discover those hidden cases to get the treatment as early as possible.
Presenter: Doctor for those who are listening in I'm sure they would like to know though what are the symptoms that families should actually look for when and when should they actually seek testing?
Dr. Aung: Oh the usual TB symptoms are like cough, fever, night sweat, weight loss and they are having like haemoptysis sort of like coughing up blood. So this is a usual TB symptoms that we used to rely on and that's why we also utilise it. But at the same time like as I said earlier like half more than half of the people that we have diagnosed do not report any of these symptoms we only discover through the chest X-rays. So it is not only that we have to rely on the symptoms are developing at the stage which is already maybe late. So whenever there is a contact of TB or whenever there is someone in your household with the TB we have to diagnose we have to screen for the whole the household so something like that so of course symptoms are there but we should not wait for the symptoms for the until very late and we have to have like a sort of like community-wide screening to know the prevalence since earlier.
Presenter: And how has the approach been like what are the results that you've been seeing so far? So we know that initially it was quite [inaudible] that we we know that but we understand at the end like it is possible and feasible to do the community screening in such kind of resource limited setting in Daru and we have achieved a high uptake of screening and then we have found like hundreds of TB cases during this screening. So at the end like this is a significant achievement and this is something that we prove that it's possible to do in such kind of community as like in Daru.
Presenter: Nice to hear. Okay. Well Doctor really could this community-wide approach that you're doing with the SWEEP-TB become maybe a model for the rest of the Pacific?
Dr. Aung: We are trying to do these things and in this community because the TB is high and it's a challenge and then we also knew that this is feasible and possible to do it in such kind of community. So that could be a model that we can we can further spread not only in PNG and Daru Western Province that's also about setting which is applicable to at the same time like we can also uh understand the context in the different locations and then modify a bit to expand this activity to other places. We also require like continuous investment for the further screening.
Presenter: Beautiful. Well, some great work that you are doing there doctor and really appreciate uh that you've been able to come on the show and share about the SWEEP-TB. Again, we just want to say thank you uh for coming on the show.
Dr. Aung: Thank you so much for having a chance uh to speak about that and thank you.
Presenter: Appreciate it. That is Burnet Institute Tuberculosis Specialist Dr Aung Aung here on Pacific Beat.
Objective
The project aims to substantially reduce tuberculosis (TB) incidence (case notification) in the population of Daru.
It will do this through the implementation of a comprehensive community-wide strategy that combines enhanced case detection, effective treatment and novel strategies for prevention.
This includes preventive therapy for multidrug-resistant/rifampicin-resistant (MDR/RR) TB.
Objective 1: Detect and treat
Implement systematic screening of all Daru residents to detect and treat prevalent disease due to drug-susceptible (DS-TB) and MDR/RR-TB.
Objective 2: Prevent
Provide TB preventive therapy or BCG vaccination to eligible Daru residents under 35 years of age to prevent infection and disease due to DS-TB and MDR/RR-TB.
Objective 3: Evaluation and knowledge transfer
Evaluation of the intervention, conduct operational research training in TB for PNG researchers and support higher degree research student supervision.
Timeline
2022–2025.
Approach
SWEEP-TB involves prospective implementation research embedded in a public health project, as part of the Western Province TB program.
The project is being implemented by the Western Provincial Health Authority (WPHA) and the Burnet Institute in collaboration with the National TB Program (NTP), the University of Papua New Guinea (UPNG), the PNG Institute of Medical Research (PNG IMR) and World Vision International.
A community advisory group (CAG) has been established to co-design community mobilisation and engagement approaches and inform health promotion and implementation.
The CAG has self-named “TB Nanito Kopia Kodu” which translates as “the voice to kill TB” in Daru.
Daru residents are being screened for TB symptoms and mobile chest x-ray with artificial intelligence (CAD4TB) in addition to standard care to detect and treat active TB.
A tuberculin skin test (TST) is administered after consent from residents aged 5-34 and if positive, TB preventive therapy (TPT) with a novel regimen of 6 months of isoniazid and levofloxacin (6Hlfx) to cover booth MDR/RR-TB and drug-susceptible (DS) TB is offered.
Those <35 years without TB disease or infection are offered BCG if not previously vaccinated.
Operational mixed-methods research will evaluate the impact, acceptability, feasibility and cost-effectiveness.
The intervention will build on the local leadership, programmatic experience and platform of innovation that has been established in Daru. Ongoing engagement and placing the affected community at the centre of the response remains critical to success.
Evaluation of the intervention will be conducted through operational research projects delivered through Burnet’s established SORT-IT partnership (Structured Operational Research Training Initiative) with capacity building and knowledge transfer to PNG researchers.
The project will strengthen the health system and workforce. SWEEP-TB complements and is co-funded by an established Burnet project, Reducing the Impact of Drug-Resistant TB (RID-TB) in Western Province, which strengthens the health system and provides technical assistance to the WPHA TB program to respond to TB.
Community impact
The significant individual health and health system burden of ongoing TB and MDR/RR-TB transmission in Daru is a compelling rationale for the potential benefit of the community-wide approach to detect, treat and prevent DS- and MDR/RR-TB.
High rates of uptake, adherence and treatment completion will be critical for effectiveness of the intervention and therefore a community-centred approach is key.
The study aims to be as inclusive as possible. All eligible members of the community will be actively encouraged to participate through community engagement, education and the informed consent process.
This will include priority groups such as age (children, adolescents and older persons), pregnant women, people living with disabilities (including cognitive impairment and mental illness) and people living with HIV.
Early detection and treatment of TB (active and latent) can reduce TB transmission in the community, and there is a broader benefit in increasing knowledge and awareness of TB.
Specific individual benefits include the diagnosis and treatment of TB disease for those not yet identified and preventing the development of TB disease in those with latent TB infection.
Health care workers in Daru will benefit through the implementation of evidence-based practice, research and capacity strengthening initiatives that build sustainable workforce capacity.
The comprehensive community-based model of care developed through the SWEEP-TB project will generate new knowledge relevant to improving health outcomes in Daru and will have applicability to similar high transmission MDR-TB settings in PNG and elsewhere.
Resources
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SWEEP-TB Guidelines (English)
Sweeptb Guidelines ENGLISH 4 [PDF 255.2 kB] -
SWEEP-TB Guidelines (Kiwai)
Sweeptb Guidelines KIWAI 4 [PDF 247.9 kB] -
SWEEP-TB flipchart
Sweeptb FLIPCHART 4 [PDF 2.3 MB]
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TB Ko'omiriti Kodu (the SWEEP-TB song) by Ben Wainetti [mp3]
TB Ko'omiriti Kodu (The SWEEP TB Song) Ben Wainetti [MP3 12.0 MB]
Partners
Funding partners
- Australian Government – Medical Research Future Fund (MRFF) grant ID MRF1201008
- Supported by the Australian Government via the PNG Australia Transition to Health (PATH) Program
Collaborators
- Western Provincial Health Authority
- National Department of Health PNG
- PNG Institute of Medial Research (PNG IMR)
- University of Papua New Guinea (UPNG)
- World Vision International
Project contacts
Associate Professor Suman Majumdar
Chief Health Officer; Deputy Program Director (Health Security and Pandemic Preparedness; Know-C19); Principal Research Fellow
Project team
Associate Professor Suman Majumdar
Chief Health Officer; Deputy Program Director (Health Security and Pandemic Preparedness; Know-C19); Principal Research Fellow
Kousa Aruba
Driver and Logistics Support Officer
Dr Aung Aung
TB Specialist – Public Health
Jenny Bodolo
Peer Counsellor
Geoffrey Chan
Health Systems and Strategic Information Specialist
Homiri Dorogori
Data Officer
Professor Steve Graham
Honorary Staff
Dr Jane Greig
Co-Head, Pacific Infectious Diseases (Operational Research, Surveillance and Resilience) Working Group; Senior Operational Epidemiologist
Gabbi Hamilton
Project Officer
Dr Khai Lin Huang
Co-Head Tuberculosis Elimination and Implementation Science, Senior Research Fellow
Billy Inkharm
IT/Data Entry Officer
Dr Shahidul Islam
Deputy Country Director for Programs, Papua New Guinea; TB Specialist - Public Health
Kyrol Kaisan
Health Promoter
Tess Keam
Social Worker
Igiam Krangaie
TB Nursing Officer, Tuberculosis Elimination & Implementation Science
Dr Rowan Martin-Hughes
Senior Research Officer
Dr Tafireyi Marukutira
TB Specialist – Public Health
Christopher Masah
Registered Nursing Officer (RID TB Nurse)- Public Health Team
Naomi Pank
Public Health Nursing Specialist, Co-Lead SWEEP-TB Project
Nazzy Ruhi
Peer Counsellor
Desmond Samson
Peer Counsellor
Iru Tofinga
Peer Counsellor
Scott Umali
Research Officer
Rudy Viriu
Senior Data Entry Officer