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Our people

Associate Professor Paul Gilson

Deputy Discipline Head, Life Sciences; Co-Head, Malaria Virulence and Drug Discovery Group; Head of Burnet Cell Imaging Facility

Taking students

Working groups

paul.gilson@burnet.edu.au
+61385062481
Associate Professor Paul Gilson

Background

Paul Gilson is a molecular biologist primarily interested in how malaria parasites invade and thrive in human red blood cells and avoid host immunity.

Improving our understanding of these basic cellular processes will greatly accelerate our efforts to develop new drugs and vaccines to combat this devastating disease.

Awards

  • 2019: Fenner Award, Burnet Institute. Awarded for outstanding contribution towards the Institute’s mission
  • 2012: Gust-McKenzie medallist, Burnet Institute

Positions

  • Co-lab head of the Gilson/Crabb laboratory
  • Co-head, Malaria Virulence and Drug Discovery Group
  • Head of Burnet’s Cell Imaging Facility.

Burnet publications

View 133 more
16 Apr 2025

Review 1: "Prodrug Activation in Malaria Parasites Mediated by An Imported Erythrocyte Esterase, Acylpeptide Hydrolase (APEH)"

Paul R. Gilson

16 Apr 2025

Review of "Prodrug Activation in Malaria Parasites Mediated by An Imported Erythrocyte Esterase, Acylpeptide Hydrolase (APEH)"

Paul R. Gilson

30 Sep 2024

Author Correction: Aryl amino acetamides prevent Plasmodium falciparum ring development via targeting the lipid-transfer protein PfSTART1

Nature Communications

Madeline G. Dans, Coralie Boulet, Somya Mehra, Zahra Razook, Dawson B. Ling, Thorey K. Jonsdottir, Alyssa E. Barry, Brendan S. Crabb, Paul R. Gilson

Open access

Current projects

Discovering novel antimalarials to block parasite invasion of human cells

Discovering novel antimalarials to block parasite invasion of human cells

Drugs are the main weapons used to combat malaria infection. However, parasites are becoming resistant and new medicines and drug targets are needed.

Understanding how malaria parasites become resistant to drugs
Open to students

Understanding how malaria parasites become resistant to drugs

This project aims to understand how novel mutations will affect malaria parasites from West Africa.

Past projects

Discovering novel antimalarials to block parasite virulence

Discovering novel antimalarials to block parasite virulence

Drugs are the main weapons used to combat malaria infection, but parasites are becoming resistant and new medicines and drug targets are needed.

Drug resistance and mechanism of action studies

Drug resistance and mechanism of action studies

We work with medicinal chemists to develop new antimalarials that are effective against already multi-drug resistant parasites.

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