Contacts

Doctor Lachlan Gray

Senior Research Officer, Churchill Laboratory

Background

Dr Lachlan Gray is a Senior Research Officer working in the HIV Neuropathogeneis Laboratory at the Burnet Institute. He trained as a molecular virologist and has research interests in HIV entry, replication, and latency. More specifically his current research addresses the following areas:

  • How HIV enters cells of the immune system with a focus on HIV entry into brain cells
  • How HIV replicates within brain cells
  • The role of HIV brain infection in the establishment of viral reservoirs and implications for HIV cure research
  • Evaluating the use of HIV cure drugs in the context of brain infection
  • Effects of antiviral drugs that target virus entry in the brain
  • How HIV infection of the brain leads to HIV dementia

Lachlan Gray completed his Bachelor of Science degree at the University of Melbourne, Australia, majoring in Virology, Immunology and Genetics in 2002. In 2003 he undertook his Honours, studying at the Burnet Institute, Melbourne, Australia, under the supervision of Prof. Paul Gorry, analyzing viral evolution in the Sydney Blood Bank Cohort of HIV-1 long-term non-progressors. Lachlan worked as a Research Assistant (RA) in the Gorry lab in 2004 contributing to various projects. Following his RA year, he commenced his PhD in 2005 under the supervision of Prof. Paul Gorry and A/Prof. Melissa Churchill, also based at the Burnet Institute. The title of his thesis was “Viral determinants of HIV-1 neurotropism and neurovirulence”. Following completion of his PhD in 2009 he commenced a Postdoctoral position at Monash University, Melbourne, Australia in 2010 under the supervision of Prof. Steve Wesselingh. He’s since returned to the Burnet in his current role as Senior Research Officer, working within the Churchill Lab. His postdoctoral studies mainly concentrate on HIV infection of the CNS and its importance to the establishment of a viral reservoir in the CNS and the development of HIV-associated dementia.

Lachlan has authored more than 36 peer-reviewed journal articles (11 as first/senior author) and presented at many prominent national and international conferences. He received the prestigious Dora Lush Biomedical Postgraduate Scholarship (NHMRC) to support him during his PhD and was also awarded a highly competitive Australian-based Postdoctoral Training Fellowship (NHMRC) in 2010 to support his Postdoctoral studies. During his short scientific career he has been awarded multiple prizes and awards (n=30), totalling more than $55,000. He is an active member of the scientific community and previously held the position of President and Chair of the AMREP Early-Mid Career Research Committee at AMREP. He also served as Editor for the ECRTimes Newsletter for the two years and helped convene several scientific workshops and conferences.

Funding

  • 2015-2016: Australian Centre for HIV & Hepatitis Research EOI, “Clinically validating the first suite of genotypic prognostic tropism tests for non-B HIV-1 subtypes”. Role: CIA. A$171,250
  • 2011-2013: Australian Centre for HIV & Hepatitis Research EOI, “Quantitative, Real-time HIV Neutralisation Assay”. Role: CIB. A$192,500
  • 2010-2013: NHMRC Australian Biomedical Postdoctoral Fellowship. Role: CIA. A$305,000
  • 2006-2008: NHMRC Dora Lush Biomedical Postgraduate Scholarship. Role: CIA. A$53,000
  • 2005-2006: Melbourne Research Scholarship (MRS), The University Of Melbourne. Role: CIA. A$18,000

Positions

  • 2014-present: Senior Postdoctoral Fellow, Churchill Lab, Burnet Institute, Australia
  • 2014-present: Adjunct Research Fellow, Department of Infectious Disease, Monash University, Australia
  • 2010-2013: NHMRC Postdoctoral Fellow, HIV Neuropathogenesis Laboratory, Monash University, Victoria, Australia
  • 2010-2013: Honorary Postdoctoral Fellow, Burnet Institute, Australia
  • 2009: Postdoctoral Fellow, HIV Neuropathogenesis Laboratory, Burnet Institute, Australia
  • 2005-2008: Part-time Research Assistant, HIV Molecular Pathogenesis Laboratory, Burnet Institute, Australia
  • 2004: Research Assistant, HIV Molecular Pathogenesis Laboratory, Burnet Institute, Australia

Qualifications

  • 2009: Doctor of Philosophy, University of Melbourne, Victoria, Australia
  • 2003: BSc (Hons), University of Melbourne, Australia
  • 2002: BSc, University of Melbourne, Australia

Awards

  • 2014: IAS “Towards an HIV Cure” Symposium Scholarship 2014
  • 2014: Australian Academy of Science sponsored delegate, 6th HOPE Meeting with Nobel Laureates
  • 2013: Burnet Prize for Infectious Diseases Research, Alfred Week Research Poster Display
  • 2013: CASS Foundation Travel Grant 2013
  • 2013: International AIDS Society Scholarship 2013
  • 2013: IAS “Towards an HIV Cure” Symposium Scholarship 2013
  • 2013: IAS/ANRS Young Investigator Award - Special HIV Cure Prize
  • 2012: AIDS 2012 International Scholarship
  • 2012: IAS “Towards an HIV Cure” Symposium Scholarship
  • 2012: IAS “Towards an HIV Cure” Rapporteur Support.
  • 2012: Monash, School Of Biomedical Sciences Travel Grant
  • 2012: ASHM 2012 Conference Scholarship
  • 2012: Burnet Prize for Infectious Diseases (1st Prize), Alfred Week Research Poster Display
  • 2012: Geoffrey Connard Travel Fellowship 2012
  • 2012: Ian Potter Foundation Travel Grant 2012
  • 2011: International AIDS Society Scholarship, IAS.
  • 2011: Monash, School Of Biomedical Sciences Travel Grant
  • 2011: Fresh Science Finalist
  • 2010: Burnet Institute Travel Award, Harold Mitchell Foundation Postdoctoral Travel Fellowship
  • 2010-2013: NHMRC Australian Biomedical Postdoctoral Fellowship.
  • 2010: Investigator in Training Trainee Travel Grant, ISNV.
  • 2010: Gilead Early Career Investigator award for best ECR presentation, ACH2.
  • 2009: Young Investigator Award, CROI.
  • 2008: Burnet Prize for Infectious Diseases (2nd Prize), Alfred Week Research Poster Display.
  • 2008: Student Research Medal (Bronze), ACH2.
  • 2008: Young Investigator Award, CROI.
  • 2007: International AIDS Society Scholarship, IAS.
  • 2006-2008: NHMRC Dora Lush Biomedical Postgraduate Scholarship.
  • 2006: Keystone Symposia Scholarship, HIV Keystone Symposium.
  • 2005-2006: Melbourne Research Scholarship (MRS), University of Melbourne.
  • 2005: Roche Award, Burnet Institute.
  • 2005: Award for most outstanding student presentation, ACH2.
  • 2003: Undergraduate and Junior Researcher Support Awards in HIV and Hepatitis, ASHM.

Projects (1)

Publications (38)

2015 (4)

2014 (3)

2013 (10)

2012 (1)

2011 (5)

2010 (5)

2009 (1)

2008 (1)

2007 (2)

2006 (3)

2005 (1)

2004 (2)

Square_gray_lachlan

Contact Details

Telephone

+61392822193

Mobile

+61416148377

Email

lachlang@burnet.edu.au