The two TPPs discussed in this survey have been formulated to meet the need for novel medicines for the prevention and management of preterm birth. Spontaneous preterm labour accounts for up to 50% of preterm births. Preterm birth is the leading cause of neonatal mortality, accounting for 35% of neonatal deaths globally. Preterm newborns that survive are at an increased risk of a number of short- and long-term adverse health outcomes, including chronic lung disease, and neurological, visual and auditory disabilities.
There are currently very few effective medicines for preventing preterm birth in women at risk. Some tocolytic agents are available that can prolong pregnancy for 2 to 7 days in women experiencing spontaneous preterm labour, however there is a lack of evidence that current treatments improve substantive fetal and neonatal health outcomes. There is an urgent need for new tocolytics that can prolong pregnancy and reduce the adverse perinatal outcomes associated with preterm birth.
Your views on medicines for preterm birth.
This page contains draft documents of two TPPs for
1) the prevention of preterm birth and
2) the treatment of preterm labour for public consultation.
If you wish to submit a response, please email firstname.lastname@example.org
For your information, all the comments you provide will be treated as non-identifiable, which means that we will not attribute these comments to you by name, nor will anything that could identify you be released outside of our study team.
- Gates Foundation
Partners + Collaborators
- Concept Foundation
Meet the project team. Together, we are translating research into better health, for all.
Doctor Annie McDougallResearch Officer
Dr Annie McDougall completed her PhD in 2012, investigating molecular factors involved in fetal lung development...
Professor Joshua VogelPrincipal Research Fellow; Deputy Discipline Head, International Development; Co-Head, Global Women's and Newborn's Health Group
Joshua is a perinatal epidemiologist and public health researcher. He is a Principal Research...
Lily AboudResearch Assistant
Lily commenced working as Research Assistant n the Global Women' and Newborn's Health Working Group, after...