We aim to increase our understanding of bat retroviruses to address public health and global infectious disease threats a well as the interplay between bat antiviral factors and bat viruses to understand how bats harbour viruses without showing clinical signs of disease.
The host range of HPG will be determined by experimental infection of primary cells and cell lines from different species. Ability of bat antiviral factors to inhibit virus replication, and their mechanism of action, will be performed in cell culture-based assays.
Bats can harbour viruses without showing clinical signs of disease. Understanding how bats can co-exist with viruses can hold the key to treating viral infections in other hosts including humans. This project will also increase our fundamental understanding of bat retroviruses and could have public health implications, as bats are hunted for bush meat in many countries.
- Dr Michelle Baker
- Dr Glenn Marsh
- Dr Ina Smith
- Dr Sinead Williams
- Mary Tachedjian
- Professor Jie Cui
- Professor Andrew Cunningham
Meet the project team. Together, we are translating research into better health, for all.
PublicationsVIEW ALL RESEARCH
Hayward JA, Tachedjian M, Johnson A, Irving AT, Gordon TB, Cui J, Nicolas A, Smith I, Boyd V, Marsh GA, Baker ML, Wang LF, Tachedjian G
- Journal of virology
- 29 Sep 2022
Hayward JA, Tachedjian G
- 07 Sep 2021
Hayward JA, Tachedjian M, Kohl C, Johnson A, Dearnley M, Jesaveluk B, Langer C, Solymosi PD, Hille G, Nitsche A, Sánchez CA, Werner A, Kontos D, Crameri G, Marsh GA, Baker ML, Poumbourios P, Drummer HE, Holmes EC, Wang LF, Smith I, Tachedjian G
- Proceedings of the National Academy of Sciences of the United States of America
- 13 Apr 2020
Hayward JA, Tachedjian M, Cui J, Cheng AZ, Johnson A, Baker ML, Harris RS, Wang LF, Tachedjian G
- Molecular biology and evolution
- 10 Jun 2019
Hayward JA, Tachedjian M, Cui J, Field H, Holmes EC, Wang LF, Tachedjian G
- 27 Mar 2013