Associate Professor Nick Scott
Head, Modelling and Biostatistics
Working groups

Background
Associate Professor Nick Scott, BSc (hons), PhD (Mathematics) is the Head of Modelling & Biostatistics at the Burnet Institute, an Adjunct Senior Research Fellow at Monash University, and an NHMRC Emerging Leader Fellow.
He leads a team of modellers who work across a number of infectious diseases and public health problems including: COVID-19; Hepatitis C; Hepatitis B; HIV; Tuberculosis; Malaria; Nutrition; Maternal, Newborn and Child health; Adolescent Health. His work aims to produce evidence to support decision and policy making, and includes epidemic and economic modelling, cost-effectiveness and return on investment analyses, resource optimisation analyses and statistical analyses.
A/Prof Scott and his team are consultants to the World Bank, Gates Foundation, Global Fund, United Nations Population Fund and the WHO, and are members of international HIV, TB, malaria and nutrition modelling consortiums.
Qualifications
- 2012: PhD in Mathematics, The University of Melbourne
- 2008: BSc (Hons), The University of Melbourne
Awards
- 2022: NHMRC Emerging Leader Fellowship
- 2021: Gust-McKenzie Medal
- 2016: Harold Mitchell Foundation Postdoctoral Travel Fellowship
- 2014-15: Jim and Margaret Beever Fellowship
- 2008-2011: Australian Postgraduate Award
- 2007: University of Melbourne Honours Scholarship
Positions
- 2020-ongoing: Head of Modelling and Biostatistics, Burnet Institute
- 2015-ongoing: Adjunct Senior Research Fellow, Monash University
- 2013-2020: Econometrician, Burnet Institute
- 2012-2013: Consultant, Transport Strategy and Operations, URS Australia
- 2008-2012: Graduate Research Student, The University of Melbourne
Reports + Policy Briefs
2021 (1)
- Modelling the Victorian roadmap (PUBLIC HEALTH REPORT) Abeysuriya R, Delport D, Sacks-Davis R, Hellard M, Scott N. Know C-19 Burnet Institute. September, 2021.
- COVASIM modelling: Impact of vaccines on epidemic outcomes. (PUBLIC HEALTH REPORT) Abeysuriya R, Hellard M, Scott N. Know-C19 Burnet Institute. June, 2021.
2020 (1)
- Estimating risks associated with early reopening in Victoria. (Policy Brief prepared for the Victorian Department of Health and Human Services) Abeysuriya R, Delport D, Hellard M, Scott N. Know-C19 Hub. September, 2020.
Reports and other work
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Modelling the impact of reducing control measures on the COVID-19 pandemic in a low transmission setting.
Abstract<br/>Objectives: To assess the risks associated with relaxing coronavirus disease 2019 (COVID-19)-related physical distancing restrictions and lockdown policies during a period of low viral transmission.<br/><br/>Design: Network-based viral transmission risks in households, schools, workplaces, and a variety of community spaces and activities were simulated in an agent-based model, Covasim.<br/><br/>Setting: The model was calibrated for a baseline scenario reflecting the epidemiological and policy environment in Victoria during March-May 2020, a period of low community viral transmission.<br/><br/>Intervention: Policy changes for easing COVID-19-related restrictions from May 2020 were simulated in the context of interventions that included testing, contact tracing (including with a smartphone app), and quarantine.<br/><br/>Main outcome measure: Increase in detected COVID-19 cases following relaxation of restrictions.<br/><br/>Results: Policy changes that facilitate contact of individuals with large numbers of unknown people (eg, opening bars, increased public transport use) were associated with the greatest risk of COVID-19 case numbers increasing; changes leading to smaller, structured gatherings with known contacts (eg, small social gatherings, opening schools) were associated with lower risks. In our model, the rise in case numbers following some policy changes was notable only two months after their implementation.<br/><br/>Conclusions: Removing several COVID-19-related restrictions within a short period of time should be undertaken with care, as the consequences may not be apparent for more than two months. Our findings support continuation of work from home policies (to reduce public transport use) and strategies that mitigate the risk associated with re-opening of social venues.
Modelling the impact of reducing control measures on the COVID-19 pandemic in a low transmission setting. -
Understanding and describing Australian illicit drug markets: Drug price variations and associated changes in a cohort of people who inject drugs.
This project was undertaken to provide a detailed understanding of the interface between the price of drugs and the behaviour of people who inject drugs (PWID) and other drug-market changes. Specifically, three major aims were to:
Understanding and describing Australian illicit drug markets: Drug price variations and associated changes in a cohort of people who inject drugs. -
Patterns of drug preference and use among people who inject drugs in Melbourne, Australia.
Background: Understanding of substitution patterns in drug using careers is limited. Between 2009 and mid-2013, the purity-adjusted price of methamphetamine declined sharply in Melbourne in absolute terms and relative to the purity-adjusted price of heroin.
Patterns of drug preference and use among people who inject drugs in Melbourne, Australia.
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Know COVID-19: Estimating risks associated with early reopening in Victoria
In this study, we use Covasim to estimate the risk of Victoria experiencing a third COVID-19 epidemic wave if Stage 4 restrictions were eased on the 14th September 2020 or two weeks later on the 28th September.
Know COVID-19: Estimating risks associated with early reopening in Victoria -
Modelling the Victorian roadmap (PUBLIC HEALTH REPORT)
COVID-19 mathematical modelling of the Victoria roadmap 2021.
Modelling the Victorian roadmap (PUBLIC HEALTH REPORT)
Burnet publications
View 150 moreOptimising TB investments in Belarus, Moldova, Kyrgyz Republic, Tajikistan and Uzbekistan: An allocative efficiency analysis
PLOS Global Public Health
Anna L. Bowring et al
Balancing Efficiency and Accuracy in Hepatitis C Rapid Antibody Testing: Insights From a Cluster Randomised Crossover Trial
Journal of Viral Hepatitis
Katherine Heath et al
Estimating the historical impact of outbreak response immunisation programmes across 210 outbreaks in low and middle-income countries
BMJ Global Health
Dominic Delport et al
Current projects
View 17 more
Optima Tuberculosis modelling
Optima Tuberculosis is an open-source model to aid the fight against TB. It combines epidemiological and economic algorithms to find the best ways to optimise resources and reduce disease.
Using mathematical models to generate evidence to support Australia’s COVID-19 responses and prepare for future pandemics
The COVID-19 pandemic has shown that effective public health responses save lives and reduce socio-economic damage. Modelling has played a critical role in public health decision-making by quantifying the risks and benefits of different policy responses. Burnet Health Modeller Dominic Delport's PhD will utilise mathematical modelling to generate evidence to support public health decision-making during outbreaks and prepare for future pandemics.

Hepatitis B modelling
We use mathematical and economic models to inform global efforts to achieving the elimination of hepatitis B as a public health threat.
Past projects
View 6 more
Modelling for evidence-based national hepatitis B testing plans
This project assessed the approach of providing hepatitis B tests to potential new migrants from endemic countries.

The elimination of hepatitis C as a global public health threat
This project addresses critical knowledge gaps in Australian and global efforts to eliminate hepatitis C as a public health threat by 2030.

Implementing the WHO Labour Care Guide to reduce the use of Caesarean section in four hospitals in India
We're helping implement the World Health Organization's (WHO) Labour Care Guide into four hospitals in India.
News and features
View 6 more
Life-saving impact of global vaccine stockpiles
New Burnet research highlights the critical role of global vaccine stockpiles in preventing widespread outbreaks of deadly diseases.

Offering COVID-19 booster vaccinations alongside influenza vaccinations could reduce hospitalisations and deaths
