Background

After completing her Bachelor of Biomedical Science degree in 2007, Jo-Anne went on to pursue an Honours degree in the laboratory of Professor Ray Norton at the Walter & Eliza Hall Institute (WEHI), to study the structural interactions of malaria antigens.

In 2009, she joined Professor James Beeson’s group at WEHI as a PhD student before moving with the rest of the group to the Burnet Institute. Her PhD project focused on understanding the significance of human antibodies to Plasmodium falciparum surface antigens and their role in protective immunity.

Jo-Anne completed her PhD and is currently working as a post-doctoral scientist under the supervision of Professor Beeson and Professor Brendan Crabb, with a particular focus on naturally acquired immunity to Plasmodium falciparum gametocyte antigens.

Qualifications

• 2012: Doctor of Philosophy, University of Melbourne
• 2008: Bachelor of Science (Honours), University of Melbourne
• 2007: Bachelor of Biomedical Science, University of Melbourne

Awards

• 2012: AMREP ECR Symposium, Best Poster Prize
• 2012: Molecular Approaches to Malaria, Best Poster Prize
• 2011: OzEMalaR Australia travel grant to the London School of Hygiene and Tropical Medicine
• 2011: Australian Society for Parasitology Annual Conference, ASP Student Travel Grant
• 2011: Lorne Infection and Immunity, Best Poster Prize

Publications (12)

2017 (3)

• Patterns of protective associations differ for antibodies to P.falciparum-infected erythrocytes and merozoites in immunity against malaria in children.
  Chan JA, Stanisic DI, Duffy MF, Robinson LJ, Lin E, Kazura JW, King CL, Siba PM, Fowkes FJ, Mueller I, Beeson JG
  Eur J Immunol. 2017 Aug; Epub ahead of print
• The exported chaperone Hsp70-x supports virulence functions for Plasmodium falciparum blood stage parasites.
  Charnaud SC, Dixon MWA, Nie CQ, Chappell L, Sanders PR, Nebl T, Hanssen E, Berriman M, Chan JA, Blanch AJ, Beeson JG, Rayner JC, Przyborski JM, Tilley L, Crabb BS, Gilson PR
  PLoS One. 2017 Jul; 12(7):e0181656
• Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort.
  Ataide R, Ashley EA, Powell R, Chan JA, Malloy MJ, O'Flaherty K, Takashima E, Langer C, Tsuboi T, Dondorp AM, Day NP, Dhorda M, Fairhurst RM, Lim P, Amaratunga C, Pukrittayakamee S, Hien TT, Htut Y, Mayxay M, Faiz MA, Beeson JG, Nosten F, Simpson JA, White NJ, Fowkes FJ
  PNAS. 2017 Mar; 114(13):3515-3520

2016 (2)

• Infectivity of Plasmodium falciparum in malaria-naive individuals is related to knob expression and cytoadherence of the parasite.
  Stanisic DI, Gerrard J, Fink J, Griffin PM, Liu XQ, Sundac L, Sekuloski S, Rodriguez IB, Pingnet J, Yang Y, Zhou Y, Trenholme KR, Wang CY, Hackett H, Chan JA, Langer C, Hanssen E, Hoffman SL, Beeson JG, McCarthy JS, Good MF
  Infect Immun. 2016 Jul; 84(9):2689-2696
• A single point in protein trafficking by Plasmodium falciparum determines the expression of major antigens on the surface of infected erythrocytes targeted by human antibodies.
  Chan JA, Howell KB, Langer C, Maier AG, Hasang W, Rogerson SJ, Petter M, Chesson J, Stanisic DI, Duffy MF, Cooke BM, Siba PM, Mueller I, Bull PC, Marsh K, Fowkes FJ, Beeson JG
  Cell Mol Life Sci. 2016 May; 73(21):4141-4158

2014 (3)

• PTEX is an essential nexus for protein export in malaria parasites.
  Elsworth B, Matthews K, Nie CQ, Kalanon M, Charnaud SC, Sanders PR, Chisholm SA, Counihan NA, Shaw PJ, Pino P, Chan J-A, Azevedo MF, Rogerson SJ, Beeson JG, Crabb BS, Gilson PR, de Koning-Ward TF
  Nature. 2014 Jul; 511(7511):587-591
• Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates.
  Chan JA, Fowkes FJ, Beeson JG
  Cell Mol Life Sci. 2014 Apr; 71(19):3633-3657
• Sequential processing of merozoite surface proteins during and after erythrocyte invasion by Plasmodium falciparum.
  Boyle MJ, Langer C, Chan JA, Hodder AN, Coppel RL, Anders RF, Beeson JG
  Infect Immun. 2014 Jan; 82(3):924-936

2013 (1)

• PfEMP1 as a target of human immunity and a vaccine candidate against malaria.
  Beeson JG, Chan JA, Fowkes FJ
  Expert Rev Vaccines. 2013 Feb; 12(2):105-108

2012 (2)

• Platelet factor 4 and Duffy antigen required for platelet killing of Plasmodium falciparum.
  McMorran BJ, Wieczorski L, Drysdale KE, Chan JA, Huang HM, Smith C, Mitiku C, Beeson JG, Burgio G, Foote SJ
  Science. 2012 Dec; 338(6112):1348-1351
• Targets of antibodies against Plasmodium falciparum-infected erythrocytes in malaria immunity.
  Chan JA, Howell KB, Reiling L, Ataide R, Mackintosh CL, Fowkes FJ, Petter M, Chesson JM, Langer C, Warimwe GM, Duffy MF, Rogerson SJ, Bull PC, Cowman AF, Marsh K, Beeson JG
  J Clin Invest. 2012 Sep; 122(9):3227-3238

2010 (1)

• Interaction between Plasmodium falciparum apical membrane antigen 1 and the rhoptry neck protein complex defines a key step in the erythrocyte invasion process of malaria parasites.
  Richard D, MacRaild CA, Riglar DT, Chan JA, Foley M, Baum J, Ralph SA, Norton RS, Cowman AF
  J Biol Chem. 2010 May; 285(19):14815-14822

News Articles (3)

2015 (1)

• AMREP Prize for Burnet research

2014 (1)

• Behind the Microscope Discovery Tour a great hit!

2012 (1)

• Lifting malaria's deadly veil: mystery solved in quest for vaccine