Preventing malaria transmission in high-risk populations

Environmental vector control such as indoor and outdoor residual spraying, and larval source management are insufficient for reducing malaria transmission among mobile migrant populations, due to their high mobility in remote areas, and personal protection may be more appropriate for this high-risk group.

The effectiveness and acceptability of insect repellent, long-lasting insecticidal nets, behavioural change communication and insecticide-treated clothing in preventing malaria have been demonstrated, but no studies have determined the effectiveness of a package of personal vector control interventions targeted to mobile migrant populations, nor their sustainability. Furthermore, there is limited information on the biting activities of vectors in the forest in the region to inform appropriate interventions.

Objective

The aim of this research is to quantify the abundance, composition, behaviour and transmission potential of Anopheles spp. mosquitoes in the forest and farm environments where residual malaria transmission occurs, and to assess the effectiveness, acceptability, feasibility and cost-effectiveness of a personal protection package to reduce malaria transmission in populations at high risk of malaria transmission.

Timeline

2021–2024.

Approach

This multinational research project includes a comprehensive vector survey conducted in rural Vietnam using multiple mosquito capture techniques to determine vector abundance and host-seeking behaviours. Additionally, a stepped wedge cluster randomised control trial with mixed methods of a personal protection package for mobile migrant populations will be implemented in over 400 rural villages in Cambodia and Lao PDR to determine its effectiveness, acceptability and sustainability.

Community impact

This project is implemented to develop and field-test the effective personal protection package(s) for MMPs and forest goers to better cut malaria transmission in these groups; thereby contributing towards malaria elimination in GMS and broadly in the Asia-pacific region.