HOMER2 study

Hepatocellular carcinoma (HCC) incidence is increasing in Australia and is associated with high mortality. However, there is limited data on the epidemiology of liver cancer in Australia, including the impact.

Objective

The project aims to:

1. describe trends in HCC incidence and aetiology over time in Victoria
2. describe trends in mortality rates for HCC over time
3. determine factors associated with survival, including health services utilization and enrolment in liver cancer surveillance
4. describe the impact of marginalization on HCC stage at diagnosis, treatment uptake and clinical outcomes

Timeline

2012–2025.

Approach

Prospective cohort study with data linkage.

Community impact

Understanding the rapidly changing trends in the epidemiology of HCC in Victoria is essential to design effective prevention programs.

Treatment approaches to HCC are changing rapidly.

This study will provide evidence for factors that are associated with improved survival outcomes to inform cost-effectiveness modelling.