Publications & Reports

Adolescent tuberculosis.

Snow KJ, Cruz AT, Seddon JA, Ferrand RA, Chiang SS, Hughes JA, Kampmann B, Graham SM, Dood PJ, Houben RM, Denholm JT, Sawyer SM, Kranzer K


Adolescence is characterised by a substantial increase in the incidence of tuberculosis, a known fact since the early 20th century. Most of the world’s adolescents live in low-income and middle-income countries where tuberculosis remains common, and where they comprise a quarter of the population. Despite this, adolescents have not yet been addressed as a distinct population in tuberculosis policy or within tuberculosis treatment services, and emerging evidence suggests that current models of care do not meet their needs. This Review discusses up-to-date information about tuberculosis in adolescence, with a focus on the management of infection and disease, including HIV co-infection and rifampicin-resistant tuberculosis. We outline the progress in vaccine development and highlight important directions for future research.

Link to PubMed Central


  • Journal: The Lancet. Child & Adolescent Health
  • Published: 01/01/2020
  • Volume: 4
  • Issue: 1
  • Pagination: 68-79