Publications & Reports

Multiplicity of Infection Is a Poor Predictor of Village-Level Plasmodium vivax and P. falciparum Population Prevalence in the Southwest Pacific.

Koepfli C, Waltmann A, Ome-Kaius M, Robinson LJ, Mueller I
Population Health & Immunity Division, Walter & Eliza Hall Institute, Parkville, Australia.


Across 8101 individuals in 46 villages, the proportion of Plasmodium spp. multiple clone infections (0%-53.8%) did not reflect prevalence by quantitative polymerase chain reaction (qPCR; 1.9%-38.4%), except for P. vivax in Solomon Islands (P < .001). Thus this parameter was not informative to identify transmission foci. In contrast, prevalence by microscopy and qPCR correlated well.

Link to publisher’s web site


  • Journal: Open Forum Infectious Diseases
  • Published: 01/11/2018
  • Volume: 5
  • Issue: 11
  • Pagination: ofy240