Publications & Reports

Analytical evaluation of GeneXpert CT/NG, the first genetic point-of-care assay for simultaneous detection of Neisseria gonorrhoeae and Chlamydia trachomatis.

Sepehr N Tabrizi, Magnus Unemo, Daniel Golparian, Jimmy Twin, Athena E Limnios, Monica Lahra, Rebecca Guy and TTANGO Investigators including J. Ward, J.M. Kaldor, B. Donovan, D.P. Wilson, H. Wand, D. Regan, L. Causer, B. Hengel, D. Anderson, D. Whiley, M. Shephard, C.Fairley
Department of Microbiology and Infectious Diseases, The Royal Women's Hospital, Parkville, Victoria, Australia. [email protected]


GeneXpert CT/NG was evaluated with 372 characterized bacterial strains. Sensitivity of 10 genome copies/reaction was obtained for both agents. Four Neisseria mucosa and two Neisseria subflava isolates were positive for one of two gonococcal targets; however, the assay flagged all as negative. The assay was analytically highly sensitive and specific.

Link to publisher’s web site


  • Journal: Journal of Clinical Microbiology
  • Published: 01/06/2013
  • Volume: 51
  • Issue: 6
  • Pagination: 1945-1947