Publications & Reports

Do apicomplexan parasite-encoded proteins act as both ligands and receptors during host cell invasion?

Gilson PR, Crabb BS
Macfarlane Burnet Institute for Medical Research and Public Health 85 Commercial Road, Melbourne, Victoria 3004 Australia.


Apicomplexan parasites are responsible for a wide range of diseases in animals, including humans, in whom Plasmodium species cause the devastating disease malaria. Several recent discoveries now indicate that these intracellular parasites may use a conserved mechanism to infect their host cells by using parasite-encoded proteins as both parasite ligands and receptors anchored to the host cells.


  • Journal: F1000 Biology Reports
  • Published: 26/08/2009
  • Volume: 1
  • Pagination: 64


Health Issue