Publications & Reports

Surface markers of a purified peritoneal eosinophil population from Mesocestoides corti-infected BALB/c male mice.

P M Hogarth, K M Cruise, I F McKenzie, G F Mitchell

Abstract

Eosinophils of approximately 95% purity were prepared from the peritoneal cavities of BALB/c male mice infected with larval cestode, Mesocestoides corti. The alloantigenic surface marker phenotype of this cell population was shown to be H-2+Ly4+Ly5+Lyt-1-,2-,3-Ly-6-,7-Ia-Thy-1-TL-. Two of four anti-Lyt-2 sera were positive when tested on purified eosinophils by using the Staphylococcus aureus protein A sheep erythrocyte rosetting method, but absorption studies indicated that this reaction was not due to anti-Lyt-2 antibodies. Eosinophils are therefore Lyt-2-, although some Lyt-2 sera contain additional eosinophil reactive antibodies. A proportion (20 to 40%) of the population of eosinophils was positive for the Fc receptor, but all were negative for the C3 receptor and for surface immunoglobulin.

Publication

  • Journal: Journal of immunology (Baltimore, Md. : 1950)
  • Published: 01/01/1980
  • Volume: 124
  • Issue: 1
  • Pagination: 406-411

Author