Publications & Reports

Fc receptors.

Powell MS, Hogarth PM
The MacFarlane Burnet Institute for Medical Research and Public Health, Austin Health, Studley Road, Heidelberg and Department of Pathology, The University of Melbourne, Parkville 3052, Australia. mpowell@burnet.edu.au

Abstract

The aggregation of cell surface Fc receptors by immune complexes induces a number of important antibody-dependent effector functions. It is becoming increasingly evident that the organization of key immune proteins has a significant impact on the function of these proteins. Comparatively little is known, however, about the nature of Fc receptor spatiotemporal organization. This review outlines the current literature concerning human Fc receptor spatial organization and physiological function.

Publication

  • Journal: Advances in Experimental Medicine and biology
  • Published: 31/12/2008
  • Volume: 640
  • Pagination: 22-34