CT2 Study: Community-based Testing and Treatment for Hepatitis C

The CT2 Study is a effectiveness-implementation hybrid trial assessing the feasibility, acceptability, effectiveness and cost-effectiveness of a community-based testing and treatment program for hepatitis C. There are two study sites in Yangon, Myanmar: Burnet Institute Thingangyun Clinic and Myanmar Liver Foundation Than Sitt Charity Clinic. These two sites serve people who inject drugs and general population respectively.

Each site provides point-of-care hepatitis C testing using rapid diagnostic test for hepatitis C antibody and the GeneXpert HCV VL test for hepatitis C RNA (with result available in under two hours). Participants with chronic hepatitis C virus infection are then offered direct-acting antiviral therapy. Participants’ treatment work-up is conducted by the generalist doctor at the clinic, with hepatologist support available if required.

This study provides the opportunity to treat up to 450 patients for their hepatitis C in primary care; complementing the National Hepatitis Control Program’s QuickStart treatment program in the tertiary hospitals.

The results of this study will inform any potential scale-up of community-based primary care provision of hepatitis C services in Myanmar and other resource-constrained settings.


January 2019 – June 2020.
Completed intensive training 7th to 11th January 2019.
Recruitment started on the 30th of January 2019.


Myanmar Liver Foundation (partner)


Foundation of Innovative and New Diagnostic; Unitaid

Contact Details

For any general enquiries relating to this project, please contact:

Professor Margaret Hellard AM

Deputy Director (Programs); Adjunct Professor, Monash University, DEPM.