Background
KEY PROJECTS:
- Human malaria pathogenesis, both in children and in pregnant women
- Mechanisms of adhesion of malaria-infected erythrocytes to placental tissue
- Impact of malaria infection on placental functions
- Mechanisms of fetal growth restriction in malaria in pregnancy
- Maternal nutrition and immunity to malaria in pregnancy
COLLABORATIONS:
National collaborations
- University of Melbourne: Professor Stephen Rogerson
- Monash University: Professor Rod Devenish
- Australian National University: A/Prof Alexander Maier
European collaborations
- IRD, Paris, France: Professor Philippe Deloron, Professor Michel Cot and Dr Valerie Briand
- Inserm/Université de Lille, France: Professor Damien Subtil
- Centre for Medical Parasitology, Copenhagen: Professor Ali Salanti, Professor Lars Hviid, A/Prof Lea Barfod
- University of Manchester: Dr Jocelyn Glazier
International (non-European) collaborations
- University of Denver, Colorado: Professor Thomas Jansson
- University of Abomey-Calavi, Benin: Professor Achille Massougbod
Appointments
- 2012 – present: Australian Society for Medical Research (ASMR)
- 2010 – present: Victorian Infection and Immunity Network
- 2010 – present: Australian Society for Parasitology
- 2010 – present: Australian and New Zealand Placental Research Association (ANZPRA)
- 2008 – present: The American Association for the Advancement of Science (AAAS)
- 2006 – present: International Federation of Placenta Association (IFPA)
- 2005 – present: ARC/NHMRC Research Network for Parasitology
- 1999 – 2000: British Society for Parasitology
Positions
- 2005 – 2014: Senior Research Fellow, Department of Medicine, The University of Melbourne
- 2005: Post-doctoral fellow, Pasteur Institute, Paris
Qualifications
- 2005: PhD in Immunology, Institut Pasteur, Paris, France
- 2000: Honours in Parasitology, University of Lille I and Montpellier II, Institut Pasteur, Paris
- 1999: Bachelor in Cellular Biology and Physiology, University of Paris VI and University of Manchester
Awards
- 2014: Travel Award, Australian/European Malaria Research Network (OzEMalaR)
- 2013: Dyason Fellowship, University of Melbourne
- 2012: Travel Award, Australian/European Malaria Research Network (OzEMalaR)
- 2011: Travel Award, Australian/European Malaria Research Network (OzEMalaR)
- 2011: Bursary from the Australian Academy of Science “Australia-France Symposium: Showcasing Excellence in Biomedical Research”, Canberra
- 2010: ASP ECR Prize, 12th International Congress of Parasitology, Melbourne
- 2007: Fellowship, ARC/NHMRC Research Network for Parasitology
Projects (4)
Current (4)
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Burnet Microbiome Initiative
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Evaluating a highly sensitive rapid malaria diagnostic in PNG
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Healthy Mothers, Healthy Babies
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HMHB: The impact of nutrition, malaria and STIs on pregnant women and infants
Publications (28)
2018 (1)
2017 (3)
- Impaired placental autophagy in placental malaria.
Dimasuay KG, Gong L, Rosario F, McBryde E, Spelman T, Glazier J, Rogerson SJ, Beeson JG, Jansson T, Devenish RJ, Boeuf P
PLoS One. 2017 Nov; 12(11):e0187291
- Declining malaria transmission differentially impacts on the maintenance of humoral immunity to Plasmodium falciparum in children.
Mugyenyi CK, Elliott SR, Yap XZ, Feng G, Boeuf P, Fegan G, Osier FFH, Fowkes FJI, Avril M, Williams TN, Marsh K, Beeson JG
J Infect Dis. 2017 Oct; 216(7):887-898
- Inhibition of placental mTOR signaling provides a link between placental malaria and reduced birthweight.
Dimasuay KG, Aitken EH, Rosario F, Njie M, Glazier J, Rogerson SJ, Fowkes FJ, Beeson JG, Powell T, Jansson T, Boeuf P
BMC Med. 2017 Jan; 15(1):1
2016 (6)
- The global threat of Zika virus to pregnancy: epidemiology, clinical perspectives, mechanisms, and impact.
Boeuf P, Drummer HE, Richards JS, Scoullar MJ, Beeson JG
BMC Med. 2016 Aug; 14(1):112
- IFPA meeting 2015 workshop report IV: Placenta and obesity; stem cells of the feto-maternal interface; placental immunobiology and infection.
Abumaree MH, Almutairi A, Cash S, Boeuf P, Chamley LW, Gamage T, James JL, Kalionis B, Khong TY, Kolahi KS, Lim R, Liong S, Morgan TK, Motomura K, Peiris HN, Pelekanos RA, Pelzer E, Shafiee A, Lash GE, Natale D
Placenta. 2016 Aug; 48(Suppl. 1):S17-S20
- The ins and outs of phosphosignalling in Plasmodium: parasite regulation and host cell manipulation.
Carvalho TG, Morahan B, von Freyend SJ, Boeuf P, Grau G, Bustos JG, Doerig C
Mol Biochem Parasitol. 2016 May; 208(1):2-15
- Placental Responses to Changes in the Maternal Environment Determine Fetal Growth.
Dimasuay KG, Boeuf P, Powell TL, Jansson T
Front Physiol. 2016 Jan; 7:12
- Immunity to malaria in an era of declining malaria transmission.
Fowkes FJ, Boeuf P, Beeson JG
Parasitology. 2016 Jan; 143(2):139-153
- Pathogenesis of Malarial Parasites in Humans (Book Chapter)
Caroline Lin Lin Chua, Ricardo Ataíde, Alexandra J. Umbers, and Phillipe Boeuf
In: Human Emerging and Re-emerging Infections Set. Sunit K. Singh (Editor) Wiley-Blackwell. 2016 Jan; Chapter 21:399-422
2015 (4)
- Azithromycin-containing intermittent preventive treatment in pregnancy affects gestational weight gain, an important predictor of birthweight in Papua New Guinea - an exploratory analysis.
Holger W Unger, Regina A Wangnapi, Maria Ome-Kaius, Philippe Boeuf, Stephan Karl, Ivo Mueller, Stephen J Rogerson
Matern Child Nutr. 2015 Sep; Epub ahead of print
- A Robust Phagocytosis Assay to Evaluate the Opsonic Activity of Antibodies against Plasmodium falciparum-Infected Erythrocytes.
Teo A, Hasang W, Boeuf P, Rogerson S
Methods Mol Biol. 2015 Jul; 1325:145-152
- Maximizing antimalarial efficacy and the importance of dosing strategies.
Beeson JG, Boeuf P, Fowkes FJ
BMC Med. 2015 May; 13(1):110
- High numbers of circulating pigmented polymorphonuclear neutrophils as a prognostic marker for decreased birth weight during malaria in pregnancy.
Caroline Lin Lin Chua, Leanne J Robinson, Francesca Baiwog, Danielle I Stanisic, John A Hamilton, Graham V Brown, Stephen J Rogerson, Philippe Boeuf
Int J Parasitol. 2015 Feb; 45(2-3):107-111
2014 (2)
- Insight into the pathogenesis of fetal growth restriction in placental malaria: decreased placental glucose transporter isoform 1 expression.
Upeksha P Chandrasiri, Caroline L L Chua, Alexandra J Umbers, Ebbie Chaluluka, Jocelyn D Glazier, Stephen J Rogerson, Philippe Boeuf
J Infect Dis. 2014 May; 209(10):1663-1667
- Utilizing nanobody technology to target non-immunodominant domains of VAR2CSA.
Sisse B Ditlev, Raluca Florea, Morten A Nielsen, Thor G Theander, Stefan Magez, Philippe Boeuf, Ali Salanti
PLoS One. 2014 Jan; 9(1):e84981
2013 (4)
- Soluble CD163, a product of monocyte/macrophage activation, is inversely associated with haemoglobin levels in placental malaria.
Caroline Lin Lin Chua, Graham V Brown, John A Hamilton, Malcolm E Molyneux, Stephen J Rogerson, Philippe Boeuf
PLoS One. 2013 May; 8(5):e64127
- IFPA Meeting 2012 Workshop Report II: epigenetics and imprinting in the placenta, growth factors and villous trophoblast differentiation, role of the placenta in regulating fetal exposure to xenobiotics during pregnancy, infection and the placenta.
M S Ahmed, L M Aleksunes, P Boeuf, M K Chung, G Daoud, G Desoye, P Diaz, T G Golos, N P Illsley, K Kikuchi, R Komatsu, T Lao, D M Morales-Prieto, T Nanovskaya, T Nobuzane, C T Roberts, R Saffery, I Tamura, K Tamura, N G Than, M Tomi, A Umbers, B Wang, M S Weedon-Fekjaer, S Yamada, K Yamazaki, M Yoshie, G E Lash
Placenta. 2013 Mar; 34 Suppl:S6-10
- Plasmodium falciparum malaria elicits inflammatory responses that dysregulate placental amino acid transport.
Philippe Boeuf, Elizabeth H Aitken, Upeksha Chandrasiri, Caroline Lin Lin Chua, Bernie McInerney, Leon McQuade, Michael Duffy, Malcolm Molyneux, Graham Brown, Jocelyn Glazier, Stephen J Rogerson
PLoS Pathog. 2013 Feb; 9(2):e1003153
- Monocytes and macrophages in malaria: protection or pathology?
Caroline Lin Lin Chua, Graham Brown, John A Hamilton, Stephen Rogerson, Philippe Boeuf
Trends Parasitol. 2013 Jan; 29(1):26-34
2012 (1)
- Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia.
Philippe S Boeuf, Severine Loizon, Gordon A Awandare, John K A Tetteh, Michael M Addae, George O Adjei, Bamenla Goka, Jorgen A L Kurtzhals, Odile Puijalon, Lars Hviid, Bartholomew D Akanmori, Charlotte Behr
Malar J. 2012 Aug; 11:253
2011 (2)
- Relevant assay to study the adhesion of Plasmodium falciparum-infected erythrocytes to the placental epithelium.
Philippe Boeuf, Wina Hasang, Eric Hanssen, Jocelyn D Glazier, Stephen J Rogerson
PLoS One. 2011 Jun; 6(6):e21126
- Placental malaria-associated inflammation disturbs the insulin-like growth factor axis of fetal growth regulation.
Alexandra J Umbers, Philippe Boeuf, Caroline Clapham, Danielle I Stanisic, Francesca Baiwog, Ivo Mueller, Peter Siba, Christopher L King, James G Beeson, Jocelyn Glazier, Stephen J Rogerson
J Infect Dis. 2011 Feb; 203(4):561-569
2008 (1)
- Placental hypoxia during placental malaria.
Philippe Boeuf, Aimee Tan, Cleofe Romagosa, Jane Radford, Victor Mwapasa, Malcolm E Molyneux, Steven R Meshnick, Nicholas H Hunt, Stephen J Rogerson
J Infect Dis. 2008 Mar; 197(5):757-765
2007 (2)
- V beta profiles in African children with acute cerebral or uncomplicated malaria: very focused changes among a remarkable global stability.
Severine Loizon, Philippe Boeuf, John K A Tetteh, Bamenla Goka, George Obeng-Adjei, Jorgen A L Kurtzhals, Christophe Rogier, Bartholomew D Akanmori, Odile Mercereau-Puijalon, Lars Hviid, Charlotte Behr
Microbes Infect. 2007 Sep; 9(11):1252-1259
- New approaches to pathogenesis of malaria in pregnancy.
S J Rogerson, P Boeuf
Parasitology. 2007 Jul; 134(Pt 13):1883-1893
2006 (1)
2005 (1)
News Articles (14)
2018 (6)
2017 (3)
2016 (4)
2015 (1)
