After completing his Bachelor of Science degree in 2001 and Master of Science degree in 2003, Ben began working as a Research Assistant investigating transcriptional termination in Vaccinia virus. At the completion of this project, he resumed his studies concentrating on virology. Ben completed his PhD in Molecular Virology from Case Western Reserve University in Cleveland, Ohio, USA in 2012. His thesis research investigated an unexpected developmental defect in mice lacking the protein PACT/RAX, a dsRNA binding protein previously expected to play a role in the innate antiviral immune response.
Ben’s research is focused on investigating the role of glycans in HIV infection, specifically in identifying novel carbohydrate inhibitors of virus entry that may be developed for clinical use.
- May 2014 – Present: Research Officer, Burnet Institute, Australia
- Feb 2013 – Dec 2013: Research Officer, University of Melbourne Department of Microbiology and Immunology, Australia
- Jun 2012 – Dec 2013: Postdoctoral Researcher, Lerner Research Institute, Cleveland Clinic, USA
- Jun 2012: Doctor of Philosophy in Molecular Virology, Case Western Reserve University, USA
- Aug 2004: Master of Science in Biology, State University of New York College at Fredonia, USA
- May 2001: Bachelor of Science in Molecular Genetics, State University of New York College at Fredonia, USA
- Plasmepsin V cleaves malaria effector proteins in a distinct endoplasmic reticulum translocation interactome for export to the erythrocyte.
Marapana DS, Dagley LF, Sandow JJ, Nebl T, Triglia T, Pasternak M, Dickerman BK, Crabb BS, Gilson PR, Webb AI, Boddey JA, Cowman AF
Nat Microbiol. 2018 Aug; 3(9):1010-1022
- The malaria PTEX component PTEX88 interacts most closely with HSP101 at the host-parasite interface.
Chisholm SA, Kalanon M, Nebl T, Sanders PR, Matthews KM, Dickerman BK, Gilson PR, de Koning-Ward TF
FEBS J. 2018 Apr; 285(11):2037-2055
- Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum.
Dickerman BK, Elsworth B, Cobbold SA, Nie CQ, McConville MJ, Crabb BS, Gilson PR
Sci Rep. 2016 Nov; 6:37502
- Metabolomics-based screening of the Malaria Box reveals both novel and established mechanisms of action.
Creek DJ, Chua HH, Cobbold SA, Nijagal B, Macrae JI, Dickerman BK, Gilson PR, Ralph SA, McConville MJ
Antimicrob Agents Chemother. 2016 Oct; 60(11):6650-6663
- Missense mutation in the second RNA binding domain reveals a role for Prkra (PACT/RAX) during skull development.
Benjamin K Dickerman, Christine L White, Claire Chevalier, Valerie Nalesso, Cyril Charles, Sophie Fouchecourt, Florian Guillou, Laurent Viriot, Ganes C Sen, Yann Herault
PLoS One. 2011 Dec; 6(12):e28537
- Inhibition of RNase L and RNA-dependent protein kinase (PKR) by sunitinib impairs antiviral innate immunity.
Babal Kant Jha, Irina Polyakova, Patricia Kessler, Beihua Dong, Benjamin Dickerman, Ganes C Sen, Robert H Silverman
J Biol Chem. 2011 Jul; 286(30):26319-26326