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Targeting CLEC9A delivers antigen to human CD141<sup>+</sup> DC for CD4<sup>+</sup> and CD8<sup>+</sup>T cell recognition.

Tullett KM, Leal Rojas IM, Minoda Y, Tan PS, Zhang JG, Smith C, Khanna R, Shortman K, Caminschi I, Lahoud MH, Radford KJ

  • Journal JCI insight

  • Published 19 May 2016

  • Volume 1

  • ISSUE 7

  • Pagination e87102

  • DOI 10.1172/jci.insight.87102


T cells. Given the importance of these cellular responses for antitumor or antiviral immunity, and the superior specificity of anti-CLEC9A Abs for this DC subset, this approach warrants further development for vaccines.