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Indirect immunofluorescence assay for the detection of hepatitis A virus-specific serum immunoglobulins.

Anderson DA, Coulepis AG, Chenoweth MP, Gust ID

  • Journal Journal of clinical microbiology

  • Published 12 Aug 1986

  • Volume 24

  • ISSUE 1

  • Pagination 163-5

  • DOI 10.1128/jcm.24.1.163-165.1986


Hepatitis A virus-specific BSC-1 cells were used for the detection of serum immunoglobulins to hepatitis A virus by indirect immunofluorescence. Of 150 serum samples tested, specific immunoglobulin M was detected only in patients with serologically confirmed acute hepatitis A, while specific immunoglobulin G was detected in patients with acute or past clinical hepatitis A as well as many patients with no known history of hepatitis.