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Analytical evaluation of GeneXpert CT/NG, the first genetic point-of-care assay for simultaneous detection of Neisseria gonorrhoeae and Chlamydia trachomatis.

Tabrizi SN, Unemo M, Golparian D, Twin J, Limnios AE, Lahra M, Guy R, TTANGO Investigators

  • Journal Journal of clinical microbiology

  • Published 03 Apr 2013

  • Volume 51

  • ISSUE 6

  • Pagination 1945-7

  • DOI 10.1128/JCM.00806-13


GeneXpert CT/NG was evaluated with 372 characterized bacterial strains. Sensitivity of 10 genome copies/reaction was obtained for both agents. Four Neisseria mucosa and two Neisseria subflava isolates were positive for one of two gonococcal targets; however, the assay flagged all as negative. The assay was analytically highly sensitive and specific.