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Concurrent liver diseases in liver transplant recipients in Australia

The proportion of Australians who have more than one liver disease is increasing, with unknown impacts on clinical severity and liver-related health outcomes.

In this study, we describe the prevalence and clinical impact of concurrent liver diseases among people undergoing liver transplantation for liver cirrhosis and liver cancer in Australia and New Zealand

  1. To describe the prevalence of concurrent liver diseases among people undergoing liver transplantation for liver failure and liver cancer
  2. To determine the additional proportion of liver transplants due to hepatitis B and C when multiple liver diagnoses are included, compared with primary diagnosis only
  3. To determine the impact of concurrent liver disease on post-liver transplant survival

2020-2022

Longitudinal cohort study- analysis of the Australian and New Zealand Liver and Intestinal Transplant Registry data.

Understanding the impact of having more than one liver disease on liver-related outcomes and mortality is vital to inform clinical management of people with chronic liver disease.


Moreover, correctly attributing adverse liver outcomes to all contributing liver diseases when more than one is present is vital to guide proportionate investment and health policy development in liver disease prevention programs.

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Associate Professor Jessica Howell

Contact Associate Professor Jessica Howell for more information about this project. 

EMAIL

Funding
Partners

  • NHMRC Program Grant
  • Ramsay health program grant

Partners +
Collaborators

  • Australian and New Zealand Liver and Intestinal Transplant Consortium

Project
Team

Meet the project team. Together, we are translating research into better health, for all.