Senior Research Officer

Telephone: (03) 9282 2277
Fax: (03) 9282 2100
Email: alyssa.barry@burnet.edu.au

 

 

 

Academic Background:

1995 BSc. (Hons) University of Tasmania
1999 PhD. University of Melbourne

Previous Positions:

1999-2000  Postdoc. Bioinformatics Group, Walter and Eliza Hall Institute, Australia
2000-2004 Postdoc Malaria Epidemiology Group, Peter Medawar Building for Pathogen Research and Department of Zoology, University of Oxford, UK
2004-2006  Postdoc. Malaria Epidemiology Group, Department of Medical Parasitology, New York University, USA


Research Interests

Population genomics of malaria candidate vaccine antigen genes
Genomic and immuno-epidemiology of the major surface antigen of P. falciparum, PfEMP1
Development of high throughput molecular tools for epidemiology of infectious diseases
Bioinformatics


Significant Publications

Barry, A., Leliwa-Sytek, A., Tavul, L., Imrie, H., Migot-Nabias, F., Brown, S.M. McVean, G.A.V., Day, K.P. (2007) Population genomics of the immune evasion (var) genes of Plasmodium falciparum. PLoS Pathogens 3 (3) : e34.

Volkman SK, Lozovsky E, Barry AE, Bedford T, Bethke L, Myrick A, Day KP, Hartl DL, Wirth DF, Sawyer SA. (2007) Genomic heterogeneity in the density of noncoding single-nucleotide and microsatellite polymorphisms in Plasmodium falciparum. Gene. 387(1-2):1-6.

Barry AE, Leliwa-Sytek A, Man K, Kasper JM, Hartl DL, Day KP. (2006) Variable SNP density in aspartyl-protease genes of the malaria parasite Plasmodium falciparum. Gene. 2006 376(2):163-73.

Barry, A. (2005) Malaria epidemiology: Insights from the genome of the malaria parasite. Journal of Molecular and Genetic Medicine 1(2):76-86.

Barry AE, Leliwa A, Choi M, Nielsen KM, Hartl DL, Day KP. (2003)
DNA sequence artifacts and the estimation of time to the most recent common ancestor (TMRCA) of Plasmodium falciparum. Mol Biochem Parasitol. 130(2):143-7.

Hartl DL, Volkman SK, Nielsen KM, Barry AE, Day KP, Wirth DF, Winzeler EA. (2002) The paradoxical population genetics of Plasmodium falciparum. Trends Parasitol. 18(6):266-72.

Volkman SK, Barry AE, Lyons EJ, Nielsen KM, Thomas SM, Choi M, Thakore SS, Day KP, Wirth DF, Hartl DL. (2001) Recent origin of Plasmodium falciparum from a single progenitor. Science. 2001 293(5529):482-4.

Barry AE, Bateman M, Howman EV, Cancilla MR, Tainton KM, Irvine DV, Saffery R, Choo KH. (2000) The 10q25 neocentromere and its inactive progenitor have identical primary nucleotide sequence: further evidence for epigenetic modification. Genome Res. 10(6):832-8.

Barry AE, Howman EV, Cancilla MR, Saffery R, Choo KH. (1999) Sequence analysis of an 80 kb human neocentromere. Hum Mol Genet. 8(2):217-27.

du Sart D, Cancilla MR, Earle E, Mao JI, Saffery R, Tainton KM, Kalitsis P, Martyn J, Barry AE, Choo KH. (1997) A functional neo-centromere formed through activation of a latent human centromere and consisting of non-alpha-satellite DNA. Nat Genet. 16(2):144-53.

 

Current Collaborations:

Karen Day - New York University
Gil McVean - University of Oxford
John Reeder - Burnet Institute
Ivo Muller - Papua New Guinea Institute of Medical Research
Denise Doolan - Queensland Institute of Medical Research
James Beeson - Walter and Eliza Hall Institute

Professional Memberships:

American Society for Tropical Medicine and Hygiene
ARC/NHMRC Research Network for Parasitology

Awards:

2007-2008 Howard Florey Centenary Fellowship - NHMRC
2006-2008 Innovation Fellowship - Victorian Endowment for Science
Knowledge and Technology (VESKI)
2005 Poster Prize, Vivax Malaria Research: 2005 and Beyond, Rockville USA
2002 Merit Award, Department of Zoology, University of Oxford
2001-2003 Howard Florey Postdoctoral Fellowship – NHMRC, Royal Society, UK and Association of Commonwealth Universities.

Telephone: (03) 9282 2277
E-mail: alyssa.barry@burnet.edu.au